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DVL1 antibody - C-terminal region
Instruction Manual!
| Product name: | DVL1 antibody - C-terminal region |
| Source: | Rabbit |
| Purity: | >95% |
| Buffer Formulation: | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Applications: | WB |
| Storage: | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| UOM: | 100ug |
Rabbit anti-DVL1 polyclonal antibody - C-terminal region
Catalog Number：IC105628
Product Profile
| ProductName | Rabbit anti-DVL1 polyclonal antibody - C-terminal region |
|---|---|
| AntibodyType | Primary Antibodies |
| Immunogen |
The immunogen for anti-DVL1 antibody: synthetic peptide directed towards the C terminal of human DVL1 |
Key Feature
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | |
| Species Reactivity | |
| Concentration | 1mg/ml |
| Purification | Protein A |
Target Information
| Gene Symbol | DVL1 |
|---|---|
| Gene Synonyms |
DVL
More
MGC54245 DVL1L1 |
| Gene Full Name | Dishevelled, dsh homolog 1 (Drosophila) |
| Gene Summary |
DVL1 is a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 gene is a candidate for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1 gene. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development. Three transcript variants encoding three different isoforms have been found for this gene.
More
|
| Alternative Names |
DVL
More
MGC54245 DVL1L1 |
| MolecularWeight(MW) | 73kDa |
| Sequence | 670 amino acids |
Database Links
| Entrez Gene | 1855 |
|---|---|
| SwissProt ID | O14640-2 |
| Protein Accession | NP_004412 |
Application
-
Western blot
2.5ug/ml
Positive Control: K562 cell lysate
Additional Information
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.
