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MTF1 antibody - C-terminal region
Instruction Manual!
| Product name: | MTF1 antibody - C-terminal region |
| Source: | Rabbit |
| Purity: | >95% |
| Buffer Formulation: | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Applications: | WB |
| Storage: | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| UOM: | 100ug |
Rabbit anti-MTF1 polyclonal antibody - C-terminal region
Catalog Number：IC105595
Product Profile
| ProductName | Rabbit anti-MTF1 polyclonal antibody - C-terminal region |
|---|---|
| AntibodyType | Primary Antibodies |
| Immunogen |
The immunogen for anti-MTF1 antibody: synthetic peptide directed towards the C terminal of human MTF1 |
Key Feature
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | |
| Species Reactivity | |
| Concentration | 1mg/ml |
| Purification | Protein A |
Target Information
| Gene Symbol | MTF1 |
|---|---|
| Gene Synonyms |
ZRF
MTF-1 |
| Gene Full Name | Metal-regulatory transcription factor 1 |
| Gene Summary |
The zinc finger transcription factor MTF-1 (metal-responsive transcription factor-1) is conserved from insects to vertebrates. The major role of MTF-1 in both organisms is to control the transcription of genes involved in the homeostasis and detoxification of heavy metal ions such as Cu2+, Zn2+ and Cd2+. In mammals, MTF-1 serves at least two additional roles. First, targeted disruption of the MTF-1 gene results in death at embryonic day 14 due to liver degeneration, revealing a stage-specific developmental role. Second, under hypoxic-anoxic stress, MTF-1 helps to activate the transcription of the gene placental growth factor (PIGF), an angiogenic protein.
More
|
| Alternative Names |
ZRF
MTF-1 |
| MolecularWeight(MW) | 81kDa |
| Sequence | 753 amino acids |
Database Links
| Entrez Gene | 4520 |
|---|---|
| SwissProt ID | Q14872 |
| Protein Accession | NP_005946 |
Application
-
Western blot
5.0ug/ml
ELISA Titer: 1:2500
Positive Control: HepG2 cell lysate
Additional Information
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.
