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MVP Antibody (N-term) (Ascites)
Instruction Manual!
| Product name: | MVP Antibody (N-term) (Ascites) |
| Source: | Mouse |
| Purity: | >95% |
| Buffer Formulation: | Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
| Applications: | WB |
| Storage: | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| UOM: | 100ug |
MVP Antibody (N-term) (Ascites)
Catalog Number：IC214817
Product Profile
| Product Name | MVP Antibody (N-term) (Ascites) |
|---|---|
| Antibody Type | Primary Antibodies |
Key Feature
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 599CT2.4.1 |
| Host Species | Mouse |
| Tested Applications | |
|
WB~~1:100~1600:
|
|
| Species Reactivity | |
| Concentration | 1mg/ml |
| Purification |
Target Information
| Gene Synonyms |
LRP
|
|---|---|
| Alternative Names |
MVP
More
LRP Major vault protein Lung resistance-related protein |
| MolecularWeight(MW) | 99327 Da |
| Function |
Required for normal vault structure. Vaults are multi- subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo- cytoplasmic transport. Down-regulates INFG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases
More
|
| Tissue Specificity | Present in most normal tissues. Higher expression observed in epithelial cells with secretory and excretory functions, as well as in cells chronically exposed to xenobiotics, such as bronchial cells and cells lining the intestine. Overexpressed in many multidrug-resistant cancer cells |
| Cellular Localization | Cytoplasm. Nucleus, nuclear pore complex. Note=5% found in the nuclear pore complex. Translocates from the nucleus to the cytoplasm upon EGF treatment |
Database Links
| Entrez Gene | 9961 |
|---|---|
| Nucleotide Accession | NP_005106.2 |
Application
-
Application
MVP Antibody (N-term)(Ascites)(Cat. #AM2146a) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the MVP antibody detected the MVP protein (arrow).
| Application Notes |
WB~~1:100~1600:
|
|---|
Additional Information
| Form | Liquid |
|---|---|
| StorageInstructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.
