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MX1 Antibody (Ascites)
Instruction Manual!
| Product name: | MX1 Antibody (Ascites) |
| Source: | Mouse |
| Purity: | >95% |
| Buffer Formulation: | Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
| Applications: | WB |
| Storage: | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| UOM: | 100ug |
MX1 Antibody (Ascites)
Catalog Number：IC214819
Product Profile
| Product Name | MX1 Antibody (Ascites) |
|---|---|
| Antibody Type | Primary Antibodies |
Key Feature
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2b |
| Clone Number | 474CT4.1.5 |
| Host Species | Mouse |
| Tested Applications | |
|
WB~~1:500~16000:
|
|
| Species Reactivity | |
| Concentration | 1mg/ml |
| Purification |
Target Information
| Alternative Names |
MX1
More
Interferon-induced GTP-binding protein Mx1 Interferon-induced protein p78 Interferon-regulated resistance GTP-binding protein MxA Myxoma resistance protein 1 Myxovirus resistance protein 1 Interferon-induced GTP-binding protein Mx1 N-terminally |
|---|---|
| MolecularWeight(MW) | 75520 Da |
| Function |
Interferon-induced dynamin-like GTPase with antiviral activity against a wide range of RNA viruses and some DNA viruses Its target viruses include negative-stranded RNA viruses and HBV through binding and inactivation of their ribonucleocapsid. May also antagonize reoviridae and asfarviridae replication. Inhibits thogoto virus (THOV) replication by preventing the nuclear import of viral nucleocapsids. Inhibits La Crosse virus (LACV) replication by sequestering viral nucleoprotein in perinuclear complexes, preventing genome amplification, budding, and egress Inhibits influenza A virus (IAV) replication by decreasing or delaying NP synthesis and by blocking endocytic traffic of incoming virus particles. Enhances ER stress-mediated cell death after influenza virus infection. May regulate the calcium channel activity of TRPCs
More
|
| Tissue Specificity | Purified His-tagged MX1 protein(Fragment) was used to produced this monoclonal antibody. |
| Cellular Localization | Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, perinuclear region. Note=Binds preferentially to negatively charged phospholipids. Co-localizes with CCHFV protein N in the perinuclear region |
Database Links
| Entrez Gene | 4599 |
|---|---|
| Nucleotide Accession | NP_001138397.1 |
Application
-
Application
MX1 Antibody (Cat. #AM2061a) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the MX1 antibody detected the MX1 protein (arrow).
| Application Notes |
WB~~1:500~16000:
|
|---|
Additional Information
| Form | Liquid |
|---|---|
| StorageInstructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.
