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Mouse Bmi1 Antibody

Mouse Bmi1 Antibody Mouse Bmi1 Antibody

Instruction Manual!

Product name: Mouse Bmi1 Antibody
Source:Mouse
Purity:>95%
Buffer Formulation:Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.
Applications:WB
Storage:For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
UOM:100ug

Mouse Bmi1 Antibody

Catalog Number:IC214005

Product Profile

Product Name Mouse Bmi1 Antibody
Antibody Type Primary Antibodies

Key Feature

Clonality Monoclonal
Isotype IgG2b
Clone Number 353CT22.4.4
Host Species Mouse
Tested Applications

WB

WB~~1:200~1600:
Species Reactivity

Human

Concentration 1mg/ml
Purification

Target Information

Gene Synonyms
Bmi-1
Pcgf4
Alternative Names
Bmi1
Bmi-1
Pcgf4
Polycomb complex protein BMI-1
Polycomb group RING finger protein 4
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MolecularWeight(MW)  36708 Da
Function
Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2 (By similarity)
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Tissue Specificity Detected in most organs with high expression levels in thymus, heart, brain and testis
Cellular Localization Nucleus. Cytoplasm (By similarity).

Database Links

Entrez Gene 12151
Nucleotide Accession NP_031578.2

Application

  • Application

    Mouse Bmi1 antibody (Cat. #AM1980b) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the Mouse Bmi1 antibody detected the Mouse Bmi1 protein (arrow).

Application Notes
WB~~1:200~1600:

Additional Information

Form Liquid
StorageInstructions  For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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