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Mouse Irgm1 Antibody (C-term) (Ascites)
Instruction Manual!
| Product name: | Mouse Irgm1 Antibody (C-term) (Ascites) |
| Source: | Mouse |
| Purity: | >95% |
| Buffer Formulation: | Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
| Applications: | WB |
| Storage: | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| UOM: | 100ug |
Mouse Irgm1 Antibody (C-term) (Ascites)
Catalog Number：IC214198
Product Profile
| Product Name | Mouse Irgm1 Antibody (C-term) (Ascites) |
|---|---|
| Antibody Type | Primary Antibodies |
Key Feature
| Clonality | Monoclonal |
|---|---|
| Isotype | IgM |
| Clone Number | 403CT8.5.5 |
| Host Species | Mouse |
| Tested Applications | |
|
WB~~1:1000~16000:
|
|
| Species Reactivity | |
| Concentration | 1mg/ml |
| Purification |
Target Information
| Gene Synonyms |
Ifi1
More
Iigp3 Irgm |
|---|---|
| Alternative Names |
Irgm1
More
Ifi1 Iigp3 Irgm Immunity-related GTPase family M protein 1 Interferon-inducible GTPase 3 Interferon-inducible protein 1 LPS-stimulated RAW 264.7 macrophage protein 47 |
| MolecularWeight(MW) | 46552 Da |
| Function |
Putative GTPase which is required for IFNG-mediated clearance of acute protozoan and bacterial infections. Functions in innate immune response probably through regulation of autophagy. May regulate proinflammatory cytokine production and prevent endotoxemia upon infection. Required for macrophage motility and possibly also for adhesion
More
|
| Tissue Specificity | Expressed in lung and primary macrophages. |
| Cellular Localization | Golgi apparatus membrane. Cell membrane. Cytoplasmic vesicle, phagosome membrane. Cytoplasmic vesicle, autophagosome membrane. Lysosome membrane. Late endosome membrane Cell projection, phagocytic cup. Note=Behaves like an integral membrane protein. Recruited to the plasma membrane around forming phagocytic cups, it remains associated with maturing phagosomes Association with phagosomes is dependent on nucleotide-binding but is IFNG-independent. Preferentially associated with cis- and medial-Golgi. Also detected in late endosomes and lysosomes |
Database Links
| Entrez Gene | 15944 |
|---|---|
| Nucleotide Accession | NP_032352.1 |
Application
-
Application
Mouse Irgm1 Antibody (Cat. #AM2003a) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the IRGM1 antibody detected the IRGM1 protein (arrow).
| Application Notes |
WB~~1:1000~16000:
|
|---|
Additional Information
| Form | Liquid |
|---|---|
| StorageInstructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.
