DDIT3 Antibody - N-terminal region
Product name: | DDIT3 Antibody - N-terminal region |
Source: | Rabbit |
Purity: | >95% |
Buffer Formulation: | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Applications: | WB |
Storage: | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
UOM: | 100ug |
Rabbit anti-DDIT3 Antibody - N-terminal region
Catalog Number:IC105417
Product Profile
ProductName | Rabbit anti-DDIT3 Antibody - N-terminal region |
---|---|
AntibodyType | Primary Antibodies |
Immunogen |
The immunogen for Anti-DDIT3 antibody is: synthetic peptide directed towards the N-terminal region of Human DDIT3 |
Key Feature
Clonality | Polyclonal |
---|---|
Isotype | IgG |
Host Species | Rabbit |
Tested Applications | |
Species Reactivity | |
Concentration | 1mg/ml |
Purification | Affinity purified |
Target Information
Gene Symbol | DDIT3 |
---|---|
Gene Full Name | DNA-damage-inducible transcript 3 |
Gene Summary |
This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.
More
|
MolecularWeight(MW) | 21kDa |
Sequence | 192 amino acids |
Database Links
Entrez Gene | 1649 |
---|---|
SwissProt ID | F8VS99 |
Protein Accession | NP_001181985 |
Application
-
Western blot
Host: Rabbit
Target Name: DDIT3
Sample Tissue: Stomach Tumor lysates
Antibody Dilution: 1.0ug/ml
Additional Information
Form | Liquid |
---|---|
Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.