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CREBL1 antibody - middle region
Instruction Manual!
| Product name: | CREBL1 antibody - middle region |
| Source: | Rabbit |
| Purity: | >95% |
| Buffer Formulation: | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Applications: | WB |
| Storage: | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| UOM: | 100ug |
Rabbit anti-CREBL1 polyclonal antibody - middle region
Catalog Number：IC105414
Product Profile
| ProductName | Rabbit anti-CREBL1 polyclonal antibody - middle region |
|---|---|
| AntibodyType | Primary Antibodies |
| Immunogen |
The immunogen for anti-CREBL1 antibody: synthetic peptide directed towards the middle region of human CREBL1 |
Key Feature
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | |
| Species Reactivity | |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
Target Information
| Gene Symbol | CREBL1 |
|---|---|
| Gene Synonyms |
CREB-RP
More
FLJ10066 G13 CREBL1 |
| Gene Full Name | Activating transcription factor 6 beta |
| Gene Summary |
ATF6B(CREBL1) is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. ATF6B is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene.The protein encoded by this gene bears sequence similarity with the Creb/ATF subfamily of the bZip superfamily of transcription factors. It localizes to both the cytoplasm and the nucleus. The gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
More
|
| Alternative Names |
CREB-RP
More
FLJ10066 G13 CREBL1 |
| MolecularWeight(MW) | 77kDa |
| Sequence | 703 amino acids |
Database Links
| Entrez Gene | 1388 |
|---|---|
| SwissProt ID | Q99941 |
| Protein Accession | NP_004372 |
Application
-
Western blot
0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: Human Muscle
Additional Information
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.
