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SOX2 antibody - N-terminal region
Instruction Manual!
| Product name: | SOX2 antibody - N-terminal region |
| Source: | Rabbit |
| Purity: | >95% |
| Buffer Formulation: | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Applications: | WBIHC |
| Storage: | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| UOM: | 100ug |
Rabbit anti-SOX2 polyclonal antibody - N-terminal region
Catalog Number：IC105469
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Product Profile
| ProductName | Rabbit anti-SOX2 polyclonal antibody - N-terminal region |
|---|---|
| AntibodyType | Primary Antibodies |
| Immunogen |
The immunogen for anti-SOX2 antibody: synthetic peptide directed towards the N terminal of human SOX2 |
Key Feature
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | |
| Species Reactivity | |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
Target Information
| Gene Symbol | SOX2 |
|---|---|
| Gene Synonyms |
ANOP3
More
MCOPS3 MGC2413 |
| Gene Full Name | SRY (sex determining region Y)-box 2 |
| Gene Summary |
SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in this gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation. This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
More
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| Alternative Names |
ANOP3
More
MCOPS3 MGC2413 |
| MolecularWeight(MW) | 34kDa |
| Sequence | 317 amino acids |
Database Links
| Entrez Gene | 6657 |
|---|---|
| SwissProt ID | P48431 |
| Protein Accession | NP_003097 |
Application
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Immunohistochemical
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Western blot
Lane 1: 20ug U87 lysate Primary Antibody Dilution :
1:1000 Secondary Antibody:
Anti-rabbit-HRP Secondary Antibody Dilution:
1:2000 Color/Signal Descriptions:
SOX2 Gene Name:
Ander Matheu Fernandez, Biodonostia Institute Submitted by: -
Western blot
0.2-1 ug/ml
ELISA Titer: 1:500
Positive Control: OVCAR-3 cell lysate
Additional Information
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.
