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ETV5 antibody - N-terminal region
Instruction Manual!
| Product name: | ETV5 antibody - N-terminal region |
| Source: | Rabbit |
| Purity: | >95% |
| Buffer Formulation: | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Applications: | WB |
| Storage: | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| UOM: | 100ug |
Rabbit anti-ETV5 polyclonal antibody - N-terminal region
Catalog Number：IC105440
Product Profile
| ProductName | Rabbit anti-ETV5 polyclonal antibody - N-terminal region |
|---|---|
| AntibodyType | Primary Antibodies |
| Immunogen |
The immunogen for anti-ETV5 antibody: synthetic peptide directed towards the N terminal of human ETV5 |
Key Feature
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | |
| Species Reactivity | |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
Target Information
| Gene Symbol | ETV5 |
|---|---|
| Gene Synonyms |
ERM
|
| Gene Full Name | Ets variant 5 |
| Gene Summary |
ETV5 Contains 1 ETS DNA-binding domain and belongs to the ETS family. The ETV5 gene expression is regulated by the conventional PKC (cPKC) pathway.ETV5 is subject to SUMO modification and this post-translational modification causes inhibition of transcription-enhancing activity Phosphorylated ETV5 and the actin cytoskeleton regulate CD44-mediated hyaluronan binding in myeloid cells. ERMs (ezrin/radixin/moesin) function as adaptor molecules in the interactions of adhesion receptors and intracellular tyrosine kinases. ETV5 can cooperate with c-Jun and has a role in progression of breast cancer.
More
|
| Alternative Names |
ERM
|
| MolecularWeight(MW) | 58kDa |
| Sequence | 510 amino acids |
Database Links
| Entrez Gene | 2119 |
|---|---|
| SwissProt ID | P41161 |
| Protein Accession | NP_004445 |
Application
-
Immunohistochemistry
Immunohistochemistry with Spleen tissue at an antibody concentration of 5ug/ml using anti-ETV5 antibody
-
Western blot
0.2-1 ug/ml
ELISA Titer: 1:7812500
Positive Control: Human Lung
Additional Information
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.
