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COPS5 antibody - N-terminal region
Instruction Manual!
| Product name: | COPS5 antibody - N-terminal region |
| Source: | Rabbit |
| Purity: | >95% |
| Buffer Formulation: | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Applications: | WB |
| Storage: | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| UOM: | 100ug |
Rabbit anti-COPS5 polyclonal antibody - N-terminal region
Catalog Number：IC105379
Product Profile
| ProductName | Rabbit anti-COPS5 polyclonal antibody - N-terminal region |
|---|---|
| AntibodyType | Primary Antibodies |
| Immunogen |
The immunogen for anti-COPS5 antibody: synthetic peptide directed towards the N terminal of human COPS5 |
Key Feature
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | |
| Species Reactivity | |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
Target Information
| Gene Symbol | COPS5 |
|---|---|
| Gene Synonyms |
CSN5
More
JAB1 MGC3149 MOV-34 SGN5 |
| Gene Full Name | COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis) |
| Gene Summary |
COPS5 is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors. The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
More
|
| Alternative Names |
CSN5
More
JAB1 MGC3149 MOV-34 SGN5 |
| MolecularWeight(MW) | 37kDa |
| Sequence | 334 amino acids |
Database Links
| Entrez Gene | 10987 |
|---|---|
| SwissProt ID | Q92905 |
| Protein Accession | NP_006828 |
Application
-
Western blot
Sample Type: 1. Human blood cells, pure
2. Human blood cells, partially purified
3. and 4. Human total cell extract, extraction only
Primary Dilution: 1:500
Secondary Anitbody: HRP conjugated anti-rabbit
Image Submitted By: Dr. Elah Pick
University of Haifa at Oranim
Additional Information
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.
