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OLIG2 antibody - N-terminal region
Instruction Manual!
| Product name: | OLIG2 antibody - N-terminal region |
| Source: | Rabbit |
| Purity: | >95% |
| Buffer Formulation: | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Applications: | WBIHC |
| Storage: | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| UOM: | 100ug |
Rabbit anti-OLIG2 polyclonal antibody - N-terminal region
Catalog Number：IC105367
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Product Profile
| ProductName | Rabbit anti-OLIG2 polyclonal antibody - N-terminal region |
|---|---|
| AntibodyType | Primary Antibodies |
| Immunogen |
The immunogen for anti-OLIG2 antibody: synthetic peptide directed towards the N terminal of human OLIG2 |
Key Feature
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | |
| Species Reactivity | |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
Target Information
| Gene Symbol | OLIG2 |
|---|---|
| Gene Synonyms |
BHLHB1
More
OLIGO2 PRKCBP2 RACK17 bHLHe19 |
| Gene Full Name | Oligodendrocyte lineage transcription factor 2 |
| Gene Summary |
OLIG2 is a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. OLIG2 is an essential regulator of ventral neuroectodermal progenitor cell fate. It is associated with T-cell acute lymphoblastic leukemia due to a chromosomal translocation t(14;21)(q11.2;q22). OLIG2 might play a role in learning deficits associated with Down syndrome.This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
More
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| Alternative Names |
BHLHB1
More
OLIGO2 PRKCBP2 RACK17 bHLHe19 |
| MolecularWeight(MW) | 32kDa |
| Sequence | 323 amino acids |
Database Links
| Entrez Gene | 10215 |
|---|---|
| SwissProt ID | Q13516 |
| Protein Accession | NP_005797 |
Application
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Immunohistochemical
Human Optic Nerve and Spinal CordCellular Target: Oligoden Drocyte Lineage Cells
Dilution: 1:500 -
Western blot
OLIG2 antibody - N-terminal region validated by WB using human LCL and mouse brains at 1:1000.
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Western blot
0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Transfected 293T
Additional Information
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.
