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NFYA antibody - C-terminal region
Instruction Manual!
| Product name: | NFYA antibody - C-terminal region |
| Source: | Rabbit |
| Purity: | >95% |
| Buffer Formulation: | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Applications: | WBIHC |
| Storage: | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| UOM: | 100ug |
Rabbit anti-NFYA polyclonal antibody - C-terminal region
Catalog Number：IC105298
Product Profile
| ProductName | Rabbit anti-NFYA polyclonal antibody - C-terminal region |
|---|---|
| AntibodyType | Primary Antibodies |
| Immunogen |
The immunogen for anti-NFYA antibody: synthetic peptide directed towards the C terminal of human NFYA |
Key Feature
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | |
| Species Reactivity | |
| Concentration | 1mg/ml |
| Purification | Protein A |
Target Information
| Gene Symbol | NFYA |
|---|---|
| Gene Synonyms |
HAP2
More
CBF-A CBF-B NF-YA |
| Gene Full Name | Nuclear transcription factor Y, alpha |
| Gene Summary |
NFYA is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms.
More
|
| Alternative Names |
HAP2
More
CBF-A CBF-B NF-YA |
| MolecularWeight(MW) | 37kDa |
| Sequence | 347 amino acids |
Database Links
| Entrez Gene | 4800 |
|---|---|
| SwissProt ID | P23511 |
| Protein Accession | NP_002496 |
Application
-
Immunohistochemical
-
Western blot
5.0-8.0ug/ml
ELISA Titer: 1:312500
Positive Control: Jurkat cell lysate
Additional Information
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.
