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CBFB Antibody - N-terminal region
Instruction Manual!
| Product name: | CBFB Antibody - N-terminal region |
| Source: | Rabbit |
| Purity: | >95% |
| Buffer Formulation: | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Applications: | WB |
| Storage: | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| UOM: | 100ug |
Rabbit anti-CBFB Antibody - N-terminal region
Catalog Number：IC105239
Product Profile
| ProductName | Rabbit anti-CBFB Antibody - N-terminal region |
|---|---|
| AntibodyType | Primary Antibodies |
| Immunogen |
The immunogen for Anti-CBFB antibody is: synthetic peptide directed towards the N-terminal region of Human CBFB |
Key Feature
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | |
| Species Reactivity | |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
Target Information
| Gene Symbol | CBFB |
|---|---|
| Gene Synonyms |
PEBP2B
|
| Gene Summary |
CBFB encodes a protein that is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and osteogenesis (e.g., RUNX2). The beta subunit is a non-DNA binding regulatory subunit; it allosterically enhances DNA binding by alpha subunit as the complex binds to the core site of various enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers and GM-CSF promoters.
More
|
| Alternative Names |
PEBP2B
|
| MolecularWeight(MW) | 21kDa |
| Sequence | 182 amino acids |
Database Links
| Entrez Gene | 865 |
|---|---|
| SwissProt ID | Q13951 |
| Protein Accession | NP_001746 |
Application
-
Western blot
Host: Rabbit
Target Name: CBFB
Sample Tissue: Jurkat Whole Cell lysates
Antibody Dilution: 1.0ug/ml
Additional Information
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.
