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APEX1 antibody - N-terminal region
Instruction Manual!
| Product name: | APEX1 antibody - N-terminal region |
| Source: | Rabbit |
| Purity: | >95% |
| Buffer Formulation: | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Applications: | WB |
| Storage: | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| UOM: | 100ug |
Rabbit anti-APEX1 polyclonal antibody - N-terminal region
Catalog Number：IC117461
Product Profile
| ProductName | Rabbit anti-APEX1 polyclonal antibody - N-terminal region |
|---|---|
| AntibodyType | Primary Antibodies |
| Immunogen |
The immunogen for anti-APEX1 antibody: synthetic peptide directed towards the N terminal of human APEX1 |
Key Feature
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | |
| Species Reactivity | |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
Target Information
| Gene Symbol | APEX1 |
|---|---|
| Gene Synonyms |
APE
More
APE1 APEN APEX APX HAP1 REF-1 REF1 |
| Gene Full Name | APEX nuclease (multifunctional DNA repair enzyme) 1 |
| Gene Summary |
Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein.
More
|
| Alternative Names |
APE
More
APE1 APEN APEX APX HAP1 REF-1 REF1 |
| MolecularWeight(MW) | 35kDa |
| Sequence | 318 amino acids |
Database Links
| Entrez Gene | 328 |
|---|---|
| SwissProt ID | P27695 |
| Protein Accession | NP_001632 |
Application
-
Western blot
0.2-1 ug/ml
Positive Control: MCF7 cell lysate
Additional Information
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.
