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PARP1antibody - C-terminal region
Instruction Manual!
| Product name: | PARP1antibody - C-terminal region |
| Source: | Rabbit |
| Purity: | >95% |
| Buffer Formulation: | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Note: The product is for research use only,not for use in diagnostic or therapeutic procedures. Catalog Number:OM105240 Price:$325.00 Discount Price Size: Store:In stock |
| Applications: | WB |
| Storage: | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| UOM: | 100ug |
Rabbit anti-PARP1 polyclonal antibody - C-terminal region
Catalog Number：IC106508
Product Profile
| ProductName | Rabbit anti-PARP1 polyclonal antibody - C-terminal region |
|---|---|
| AntibodyType | Primary Antibodies |
| Immunogen |
The immunogen for anti-PARP1 antibody: synthetic peptide directed towards the C terminal of human PARP1 |
Key Feature
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | |
| Species Reactivity | |
| Concentration | 1mg/ml |
| Purification | Protein A |
Target Information
| Gene Symbol | PARP1 |
|---|---|
| Gene Synonyms |
C12orf6
|
| Gene Full Name | Poly (ADP-ribose) polymerase family, member 11 |
| Gene Summary |
PARP1 encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. PARP1 can be cleaved resulting in fragements of 29 and 85 kDa.
More
|
| Alternative Names |
C12orf6
PARP1 |
| MolecularWeight(MW) | 113kDa |
| Sequence | 1014 amino acids |
Database Links
| Entrez Gene | 57097 |
|---|---|
| SwissProt ID | P09874 |
| Protein Accession | NP_001609 |
Application
-
Western blot
5.0ug/ml
Positive Control: Jurkat cell lysate
Additional Information
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.
