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ABL1 / 2 Antibody

ABL1 / 2 Antibody ABL1 / 2 Antibody

Instruction Manual!

Product name: ABL1 / 2 Antibody
Source:Rabbit
Purity:>95%
Buffer Formulation:Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Applications:WB
Storage:Store antibody at -20˚C for up to one year.
UOM:100ug

ABL1 / 2 Antibody

Catalog Number:IC269638

Product Profile

Product Name ABL1 / 2 Antibody
Antibody Type Primary Antibodies
Productdescription 
							
Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. Regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired. Phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks.1) Wang, J. Y. et al. (2000) Oncogene 19, 5643-5650. Danial, N. N. et al. (2000) Oncogene 19, 2523-2531. Brasher, B. B. et al. (2000) J. Biol. Chem. 275, 35631-35637. Pluk, H. et al. (2002) Cell 108, 247-259.
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Immunogen
ABL1/2 (Ab-393/429) antibody was raised against a peptide sequence around aa.391~395/427~431 (D-T-Y-T-A) derived from ABL1/2 .

Key Feature

Clonality Polyclonal
Host Species Rabbit
Tested Applications

WB

Western Blot: 1:500~1:1000:
Species Reactivity

HumanMouse

Concentration 1mg/ml
Purification Affinity purified

Target Information

Gene Symbol ABL1 ABL2
Alternative Names
ABL
JTK7
p150
c-ABL
v-abl
c-ABL1
bcr/abl
MAPKAPK1A
RSK1
ABL
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Molecular Weight(MW) 135, 210 kDa
Tissue Specificity This antibody detects endogenous levels of total ABL1/2 protein.

Database Links

Entrez Gene 25 / 27
Protein Accession NP_005148.2 / NP_001129472.1

Application

Application Notes
Western Blot: 1:500~1:1000:

Additional Information

Form Liquid
StorageInstructions  Store antibody at -20˚C for up to one year.
Storage Buffer Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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