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MUC1 antibody - middle region
Instruction Manual!
| Product name: | MUC1 antibody - middle region |
| Source: | Rabbit |
| Purity: | >95% |
| Buffer Formulation: | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Applications: | WB |
| Storage: | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| UOM: | 100ug |
Rabbit anti-MUC1 polyclonal antibody - middle region
Catalog Number：IC110409
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Product Profile
| ProductName | Rabbit anti-MUC1 polyclonal antibody - middle region |
|---|---|
| AntibodyType | Primary Antibodies |
| Immunogen |
The immunogen for anti-MUC1 antibody: synthetic peptide directed towards the middle region of human MUC1 |
Key Feature
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | |
| Species Reactivity | |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
Target Information
| Gene Symbol | MUC1 |
|---|---|
| Gene Synonyms |
CD227
More
EMA H23AG MAM6 PEM PEMT PUM KL-6 MUC-1 MUC-1/X MUC1/ZD MUC-1/SEC |
| Gene Full Name | Mucin 1, cell surface associated |
| Gene Summary |
MUC1 is a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is a member of the mucin family and encodes a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length nature of only some has been determined.
More
|
| Alternative Names |
CD227
More
EMA H23AG MAM6 PEM PEMT PUM KL-6 MUC-1 MUC-1/X MUC1/ZD MUC-1/SEC |
| MolecularWeight(MW) | 14kDa |
| Sequence | 159 amino acids |
Database Links
| Entrez Gene | 4582 |
|---|---|
| SwissProt ID | Q7Z550 |
| Protein Accession | NP_001037857 |
Application
-
Immunohistochemical
Human stomach
Primary Antibody Dilution :
1:200
Secondary Antibody :
Anti-rabbit-HRP
Secondary Antibody Dilution :
1:1000
Color/Signal Descriptions :
Brown: MUC1 Blue: Nucleus
Gene Name :
MUC1
Submitted by :
Dr. Sara Linden, University of Gothenburg -
Immunohistochemical
Pig stomach
Primary Antibody Dilution :
1:200
Secondary Antibody :
Anti-rabbit-HRP
Secondary Antibody Dilution :
1:1000
Color/Signal Descriptions :
Brown: MUC1 Blue: Nucleus
Gene Name :
MUC1
Submitted by :
Dr. Sara Linden, University of Gothenburg -
Western blot
0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Hela cell lysate
Additional Information
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.
