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MYC antibody - N-terminal region

MYC antibody - N-terminal region MYC antibody - N-terminal region

Instruction Manual!

Product name: MYC antibody - N-terminal region
Source:Rabbit
Purity:>95%
Buffer Formulation:phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Applications:WBIHC
Storage:Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
UOM:100ug

Rabbit anti-MYC polyclonal antibody - N-terminal region

Catalog Number:IC108597

Product Profile

ProductName  Rabbit anti-MYC polyclonal antibody - N-terminal region
AntibodyType  Tags Antibodies
Immunogen
The immunogen for anti-MYC antibody: synthetic peptide directed towards the N terminal of human MYC

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

WBIHC

Species Reactivity

BovineDogGuinea PigHumanMousePigRabbitRatSheep

Concentration 1mg/ml
Purification Protein A

Target Information

GeneSymbol  MYC
Gene Synonyms
MRTL
c-Myc
bHLHe39
More 
GeneFullName  V-myc myelocytomatosis viral oncogene homolog (avian)
Gene Summary
MYC is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this MYC gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma.The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.
More 
Alternative Names
MRTL
c-Myc
bHLHe39
More 
MolecularWeight(MW)  19kDa
Sequence 170 amino acids

Database Links

Entrez Gene 4609
SwissProt ID P01106
Protein Accession AAA88092

Application

Additional Information

Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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