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PPARGC1A antibody
Instruction Manual!
| Product name: | PPARGC1A antibody |
| Source: | Rabbit |
| Purity: | >95% |
| Buffer Formulation: | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Applications: | IF WB |
| Storage: | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| UOM: | 100ug |
Rabbit anti-PPARGC1A polyclonal antibody - N-terminal region
Catalog Number：IC105377
Product Profile
| ProductName | Rabbit anti-PPARGC1A polyclonal antibody - N-terminal region |
|---|---|
| AntibodyType | Primary Antibodies |
| Immunogen |
The immunogen for anti-PPARGC1A antibody: synthetic peptide directed towards the N terminal of human PPARGC1A |
Key Feature
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | |
| Species Reactivity | |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
Target Information
| Gene Symbol | PPARGC1A |
|---|---|
| Gene Synonyms |
LEM6
More
PGC-1(alpha) PGC-1v PGC1 PGC1A PPARGC1 |
| Gene Full Name | Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha |
| Gene Summary |
PPARGC1A is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity.The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
More
|
| Alternative Names |
LEM6
More
PGC-1(alpha) PGC-1v PGC1 PGC1A PPARGC1 |
| MolecularWeight(MW) | 91kDa |
| Sequence | 798 amino acids |
Database Links
| Entrez Gene | 10891 |
|---|---|
| SwissProt ID | Q9UBK2 |
| Protein Accession | NP_037393 |
Application
-
Immunofluorescence
Mouse retina
Primary Antibody Dilution :
1:200
Secondary Antibody :
Donkey anti rabbit-Cy3
Secondary Antibody Dilution :
1:1000
Color/Signal Descriptions :
Red: PPARGC1A
Gene Name :
PPARGC1A
Submitted by :
Dr. Joshua Sanes -
Western blot
0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Jurkat cell lysate
Additional Information
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.
