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TADA3L antibody
Instruction Manual!
| Product name: | TADA3L antibody |
| Source: | Rabbit |
| Purity: | >95% |
| Buffer Formulation: | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Applications: | WB |
| Storage: | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| UOM: | 100ug |
Rabbit anti-TADA3L polyclonal antibody - middle region
Catalog Number：IC105361
Product Profile
| ProductName | Rabbit anti-TADA3L polyclonal antibody - middle region |
|---|---|
| AntibodyType | Primary Antibodies |
| Immunogen |
The immunogen for anti-TADA3L antibody: synthetic peptide directed towards the middle region of human TADA3L |
Key Feature
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | |
| Species Reactivity | |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
Target Information
| Gene Symbol | TADA3L |
|---|---|
| Gene Synonyms |
ADA3
More
FLJ20221 FLJ21329 hADA3 NGG1 TADA3L |
| Gene Full Name | Transcriptional adaptor 3 |
| Gene Summary |
Adaptor proteins are usually required for transcriptional activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter.TADA3L is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis.Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. In addition, it associates with the tumor suppressor protein p53 and is required for full activity of p53 and p53-mediated apoptosis. At least four alternatively spliced variants have been found for this gene, but the full-length nature of some variants has not been determined.
More
|
| Alternative Names |
ADA3
More
FLJ20221 FLJ21329 hADA3 NGG1 TADA3L |
| MolecularWeight(MW) | 49kDa |
| Sequence | 432 amino acids |
Database Links
| Entrez Gene | 10474 |
|---|---|
| SwissProt ID | O75528 |
| Protein Accession | NP_006345 |
Application
-
Western blot
0.2-1 ug/ml
ELISA Titer: 1:12500
Positive Control: Jurkat cell lysate
Additional Information
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.
