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AURKA antibody

AURKA antibody AURKA antibody

Instruction Manual!

Product name: AURKA antibody
Source:Rabbit
Purity:>95%
Buffer Formulation:phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Applications:WB IHC
Storage:Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
UOM:100ug

Rabbit anti-AURKA polyclonal antibody - C-terminal region

Catalog Number:IC105231

Product Profile

ProductName  Rabbit anti-AURKA polyclonal antibody - C-terminal region
AntibodyType  Primary Antibodies
Immunogen
The immunogen for anti-AURKA antibody: synthetic peptide directed towards the C terminal of human AURKA

Key Feature

Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications

WBIHC

Species Reactivity

BovineHumanSheep

Concentration 1mg/ml
Purification Affinity purified

Target Information

Gene Symbol AURKA
Gene Synonyms
AIK
ARK1
AURA
AURORA2
BTAK
MGC34538
STK15
STK6
STK7
PPP1R47
More 
Gene Full Name Aurora kinase A
Gene Summary
AURKA is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. It is found at the centrosome in interphase cells and at the spindle poles in mitosis. This protein may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene.The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene.
More 
Alternative Names
AIK
ARK1
AURA
AURORA2
BTAK
MGC34538
STK15
STK6
STK7
PPP1R47
More 
MolecularWeight(MW)  46kDa
Sequence 403 amino acids

Database Links

Entrez Gene 6790
SwissProt ID O14965
Protein Accession NP_003591

Application

  • Immunohistochemistry

    Immunohistochemistry with Prostate tissue at an antibody concentration of 5ug/ml using anti-AURKA antibody

  • Western blot

    0.2-1 ug/ml
    ELISA Titer: 1:2500
    Positive Control: 293T cell lysate

Additional Information

Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.

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