RET antibody
Product name: | RET antibody |
Source: | Rabbit |
Purity: | >95% |
Buffer Formulation: | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Applications: | WB |
Storage: | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
UOM: | 100ug |
Rabbit anti-RET polyclonal antibody - C-terminal region
Catalog Number:IC105233
Product Profile
Product Name | Rabbit anti-RET polyclonal antibody - C-terminal region |
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Antibody Type | Primary Antibodies |
Key Feature
Clonality | Polyclonal |
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Isotype | IgG |
Host Species | Rabbit |
Tested Applications | |
Species Reactivity | |
Concentration | 1mg/ml |
Purification | Affinity purified |
Target Information
Gene Symbol | RET |
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Gene Synonyms |
CDHF12
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CDHR16 HSCR1 MEN2A MEN2B MTC1 PTC RET-ELE1 RET51 |
Gene Full Name | Ret proto-oncogene |
Gene Summary |
This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed.
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Alternative Names |
CDHF12
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CDHR16 HSCR1 MEN2A MEN2B MTC1 PTC RET-ELE1 RET51 |
MolecularWeight(MW) | 123kDa |
Sequence | 1114 amino acids |
Database Links
Entrez Gene | 5979 |
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SwissProt ID | P07949 |
Protein Accession | NP_000314 |
Application
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Western blot
Titration: 1.0 ug/ml
Positive Control: 293T Whole Cell
Additional Information
Form | Liquid |
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Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.