NR3C1 antibody
Product name: | NR3C1 antibody |
Source: | Rabbit |
Purity: | >95% |
Buffer Formulation: | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Applications: | WB |
Storage: | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
UOM: | 100ug |
Rabbit anti-NR3C1 polyclonal antibody - N-terminal region
Catalog Number:IC105256
Product Profile
ProductName | Rabbit anti-NR3C1 polyclonal antibody - N-terminal region |
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AntibodyType | Primary Antibodies |
Immunogen |
The immunogen for anti-NR3C1 antibody: synthetic peptide directed towards the N terminal of human NR3C1 |
Key Feature
Clonality | Polyclonal |
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Isotype | IgG |
Host Species | Rabbit |
Tested Applications | |
Species Reactivity | |
Concentration | 1mg/ml |
Purification | Affinity purified |
Target Information
Gene Symbol | NR3C1 |
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Gene Synonyms |
GCCR
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GCR GR GRL |
Gene Full Name | Nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
Gene Summary |
NR3C1 is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator of other transcription factors. This protein can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins. The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus. Mutations in this gene are a cause of glucocorticoid resistance, or cortisol, resistance.
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Alternative Names |
GCCR
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GCR GR GRL |
MolecularWeight(MW) | 86kDa |
Sequence | 777 amino acids |
Database Links
Entrez Gene | 2908 |
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SwissProt ID | P04150 |
Protein Accession | NP_001018086 |
Application
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Western blot
Titration: 1.0 ug/ml
Positive Control: HepG2 Whole Cell
Additional Information
Form | Liquid |
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Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.