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CCNH antibody
Instruction Manual!
| Product name: | CCNH antibody |
| Source: | Rabbit |
| Purity: | >95% |
| Buffer Formulation: | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Applications: | WB |
| Storage: | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| UOM: | 100ug |
Rabbit anti-CCNH polyclonal antibody - N-terminal region
Catalog Number：IC105308
Product Profile
| ProductName | Rabbit anti-CCNH polyclonal antibody - N-terminal region |
|---|---|
| AntibodyType | Primary Antibodies |
| Immunogen |
The immunogen for anti-CCNH antibody: synthetic peptide directed towards the N terminal of human CCNH |
Key Feature
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | |
| Species Reactivity | |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
Target Information
| Gene Symbol | CCNH |
|---|---|
| Gene Synonyms |
CAK
p34 p37 |
| Gene Full Name | Cyclin H |
| Gene Summary |
Cyclin H regulates CDK7, the catalytic subunit of the CDK- activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDC2/CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive carboxyl-terminus domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. It is involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.
More
|
| Alternative Names |
CAK
p34 p37 |
| MolecularWeight(MW) | 38kDa |
| Sequence | 323 amino acids |
Database Links
| Entrez Gene | 902 |
|---|---|
| SwissProt ID | P51946 |
| Protein Accession | NP_001230 |
Application
-
Western blot
0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Hela cell lysate
Additional Information
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.
