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FADD antibody
Instruction Manual!
| Product name: | FADD antibody |
| Source: | Rabbit |
| Purity: | >95% |
| Buffer Formulation: | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Applications: | WB |
| Storage: | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| UOM: | 100ug |
Rabbit anti-FADD polyclonal antibody - C-terminal region
Catalog Number：IC105164
Product Profile
| ProductName | Rabbit anti-FADD polyclonal antibody - C-terminal region |
|---|---|
| AntibodyType | Primary Antibodies |
| Immunogen |
The immunogen for anti-FADD antibody: synthetic peptide directed towards the C terminal of mouse FADD |
Key Feature
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | |
| Species Reactivity | |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
Target Information
| Gene Symbol | FADD |
|---|---|
| Gene Synonyms |
Mort1/FADD
|
| Gene Full Name | Fas (TNFRSF6)-associated via death domain |
| Gene Summary |
Fadd is apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis.
More
|
| Alternative Names |
Mort1/FADD
|
| MolecularWeight(MW) | 23kDa |
| Sequence | 205 amino acids |
Database Links
| Entrez Gene | 14082 |
|---|---|
| SwissProt ID | Q61160 |
| Protein Accession | NP_034305 |
Application
-
Western blot
0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: SP2/0 cell lysate
Additional Information
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.
