TNFRSF antibody
Product name: | TNFRSF antibody |
Source: | Rabbit |
Purity: | >95% |
Buffer Formulation: | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Applications: | WB |
Storage: | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
UOM: | 100ug |
Rabbit anti-TNFRSF10A polyclonal antibody - C-terminal region
Catalog Number:IC105193
Product Profile
Product Name | Rabbit anti-TNFRSF10A polyclonal antibody - C-terminal region |
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Antibody Type | Primary Antibodies |
Key Feature
Clonality | Polyclonal |
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Isotype | IgG |
Host Species | Rabbit |
Tested Applications | |
Species Reactivity | |
Concentration | 1mg/ml |
Purification | Affinity purified |
Target Information
Gene Symbol | TNFRSF10A |
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Gene Synonyms |
APO2
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CD261 DR4 MGC9365 TRAILR-1 TRAILR1 |
Gene Full Name | Tumor necrosis factor receptor superfamily, member 10a |
Gene Summary |
This is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The adaptor molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB.
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Alternative Names |
APO2
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CD261 DR4 MGC9365 TRAILR-1 TRAILR1 |
MolecularWeight(MW) | 50kDa |
Sequence | 468 amino acids |
Database Links
Entrez Gene | 8797 |
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SwissProt ID | O00220 |
Protein Accession | NP_003835 |
Application
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Western blot
Titration: 1.0 ug/ml
Positive Control: ACHN Whole Cell
Additional Information
Form | Liquid |
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Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Note: The product is for research use only,not for use in diagnostic or therapeutic procedures.