ZNF496 antibody
Product name: | ZNF496 antibody |
Source: | Rabbit |
Purity: | >95% |
Buffer Formulation: | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Applications: | WB |
Storage: | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
UOM: | 100ug |
Product Profile
ProductName | Rabbit anti-ZNF496 polyclonal antibody - middle region |
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AntibodyType | Primary Antibodies |
Immunogen |
The immunogen for anti-ZNF496 antibody: synthetic peptide directed towards the middle region of human ZNF496 |
Key Feature
Clonality | Polyclonal |
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Isotype | IgG |
Host Species | Rabbit |
Tested Applications | |
Species Reactivity | |
Concentration | 1mg/ml |
Purification | Affinity purified |
Target Information
GeneSymbol | ZNF496 |
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GeneSynonyms |
ZNF496
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Gene Full Name | Zinc finger protein 496 |
Gene Summary |
ZNF496 contains a SCAN box, a KRAB-A domain, and four consensus C2H2-type zinc fingers preceded by a unique finger derivative, referred to herein as the C2HR motif. The C2HR motif functions to mediate protein-protein interaction with the cysteine-rich (C5HCH) domain of NSD1 in a Zn(II)-dependent fashion, and when tethered to RNA polymerase II promoters, represses transcription in an NSD1-dependent manner. ZNF496 contains a novel type of zinc finger motif that functions as a docking site for NSD1 and is more than just a degenerate evolutionary remnant of a C2H2 motif.
More
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Alternative Names |
MGC15548
More
NIZP1 ZKSCAN17 ZFP496 |
MolecularWeight(MW) | 67kDa |
Sequence | 587 amino acids |
Database Links
Entrez Gene | 84838 |
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SwissProt ID | Q96IT1 |
Protein Accession | NP_116141 |
Application
-
Application
WB Suggested Anti-ZNF496 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:12500
Positive Control: PANC1 cell lysate
Additional Information
Form | Liquid |
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Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |